P5585

Palmitic acid

Manufacturer: Sigma Aldrich

CAS Number: 57-10-3

Synonym(S): 1-Pentadecanecarboxylic acid, C16:0, Cetylic acid, Hexadecanoic acid, NSC 5030, PamOH

Select a Size

Pack Size SKU Availability Price
10 G P5585-10-G In Stock ₹ 7,328.53
25 G P5585-25-G In Stock ₹ 9,298.68
100 G P5585-100-G In Stock ₹ 18,932.93

P5585 - 10 G

₹ 7,328.53

In Stock

Quantity

1

Base Price: ₹ 7,328.53

GST (18%): ₹ 1,319.135

Total Price: ₹ 8,647.665

biological source

plant (vegetable)

Quality Level

200

vapor pressure

10 mmHg ( 210 °C)

product line

BioXtra

Assay

≥99%

form

powder

technique(s)

cell culture | mammalian: suitable

impurities

≤0.0005% Phosphorus (P)≤0.1% Insoluble matter

ign. residue

≤0.1%

bp

271.5 °C/100 mmHg (lit.)

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Description

  • Application: Palmitic acid has been used:as a medium supplement in chorionic villous tissue culture form placenta[1]as a component of hormone pellet for implantation in mice ovary[2]for inducing expression of immunity-related GTPase M (IRGM) in human monocytic cell line, THP-1[3]
  • Biochem/physiol Actions: Palmitic acid (PA) is a component of membrane phospholipids (PL) and adipose triacylglycerols (TAG).[4] Elevated levels of palmitic acid contributes to the pathophysiology of atherosclerosis, type 2 diabetes mellitus, neurodegenerative diseases, obesity and cancer.[4][5] PA promotes apoptosis in the endothelial cell by modulating the p38 mitogen-activated protein kinase (MAPK) pathway and favors expression of TNF-α and reactive oxygen species accumulation.[6] PA promotes interleukin 8 (IL-8) synthesis in hepatocytes contributing to hepatic inflammation.[7] PA by interacting with toll-like receptor 4 (TLR4) induces inflammatory injury in cardiomyoctes.[8]

SAFETY INFORMATION

WGK

nwg

Flash Point(F)

235.4 °F

Flash Point(C)

113 °C

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves