111910

2-Chlorotoluene

99%

Manufacturer: Sigma Aldrich

CAS Number: 95-49-8

Synonym(S): 1-chloro-2-methylbenzene

Select a Size

Pack Size SKU Availability Price
100 G 111910-100-G In Stock ₹ 3,474.83
1 KG 111910-1-KG In Stock ₹ 10,348.70
4 KG 111910-4-KG In Stock ₹ 26,510.43

111910 - 100 G

₹ 3,474.83

In Stock

Quantity

1

Base Price: ₹ 3,474.83

GST (18%): ₹ 625.469

Total Price: ₹ 4,100.299

vapor density

4.38 (vs air)

Quality Level

100

vapor pressure

10 mmHg ( 43 °C)

Assay

99%

form

liquid

refractive index

n20/D 1.525 (lit.)

bp

157-159 °C (lit.)

mp

−36 °C (lit.)

solubility

H2O: soluble

density

1.083 g/mL at 25 °C (lit.)

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Description

  • General description: 2-Chlorotoluene can be mineralized completely by Rhodococcus, strain OCT 10 DSM 45596(T)[1]. It is used in the preparation of 3-chloro-4-methylcatechol and 4-chloro-3-methylcatechol[2]. The oxidation of 2-chlorotoluene is very well catalyzed by the enzymes: toluene dioxygenase of P. putida F1 and chlorobenzene dioxygenase from Burkholderia, strain PS12[3].
  • Application: 2-Chlorotoluene can be used as a precursor to synthesize aryl coupling products via palladium-catalyzed Negishi cross-coupling.[4] It can also be used in the Buchwald-Hartwig amination to synthesize arylamines.[5][6]

SAFETY INFORMATION

Pictograms

GHS02,GHS08,GHS07,GHS09

Signal Word

Warning

Hazard Statements

H226,H332,H361d,H410

Precautionary Statements

P202 - P210 - P233 - P273 - P304 + P340 + P312 - P308 + P313

Hazard Classifications

Acute Tox. 4 Inhalation - Aquatic Acute 1 - Aquatic Chronic 2 - Flam. Liq. 3 - Repr. 2

WGK

WGK 2

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves