141186

Chloromethyl pivalate

97%

Manufacturer: Sigma Aldrich

CAS Number: 18997-19-8

Synonym(S): POM-Cl, Pivaloyloxymethyl chloride

Select a Size

Pack Size SKU Availability Price
25 G 141186-25-G In Stock ₹ 1,515.50
100 G 141186-100-G In Stock ₹ 5,109.40

141186 - 25 G

₹ 1,515.50

In Stock

Quantity

1

Base Price: ₹ 1,515.50

GST (18%): ₹ 272.79

Total Price: ₹ 1,788.29

Quality Level

200

Assay

97%

form

liquid

refractive index

n20/D 1.417 (lit.)

bp

146-148 °C (lit.)

density

1.045 g/mL at 25 °C (lit.)

SMILES string

CC(C)(C)C(=O)OCCl

InChI

1S/C6H11ClO2/c1-6(2,3)5(8)9-4-7/h4H2,1-3H3

InChI key

GGRHYQCXXYLUTL-UHFFFAOYSA-N

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Description

  • General description: Chloromethyl pivalate reacts with sodium salt of sulbactam to yield sulbactam pivoxil[1]. It undergoes acylation reaction with 9-(2-phosphonylmethoxyethyl)adenine (PMEA) to yield bis(pivaloyloxymethyl) PMEA[2].
  • Application: Chloromethyl pivalate was used in the synthesis of pivaloyloxy methyl ester of ofloxacin as prodrug[3]. It was used as the reagent during the synthesis of an isoindoline-annulated, tricyclic sultam library via microwave-assisted, continuous-flow organic synthesis[4].

SAFETY INFORMATION

Pictograms

GHS02,GHS07

Signal Word

Warning

Hazard Statements

H226,H302 + H312 + H332,H315,H319,H335

Precautionary Statements

P210 - P280 - P301 + P312 - P303 + P361 + P353 - P304 + P340 + P312 - P305 + P351 + P338

Hazard Classifications

Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Eye Irrit. 2 - Flam. Liq. 3 - Skin Irrit. 2 - STOT SE 3

Target Organs

Respiratory system

WGK

WGK 3

Flash Point(F)

closed cup

Flash Point(C)

closed cup

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves