145289

4-Chloro-2-methylthiopyrimidine

98%

Manufacturer: Sigma Aldrich

CAS Number: 49844-90-8

Select a Size

Pack Size SKU Availability Price
10 G 145289-10-G In Stock ₹ 18,537.00
50 G 145289-50-G In Stock ₹ 63,969.30

145289 - 10 G

₹ 18,537.00

In Stock

Quantity

1

Base Price: ₹ 18,537.00

GST (18%): ₹ 3,336.66

Total Price: ₹ 21,873.66

Quality Level

200

Assay

98%

refractive index

n20/D 1.6 (lit.)

bp

139-140 °C/36 mmHg (lit.)

mp

−2 °C (lit.)

density

1.381 g/mL at 25 °C (lit.)

SMILES string

CSc1nccc(Cl)n1

InChI

1S/C5H5ClN2S/c1-9-5-7-3-2-4(6)8-5/h2-3H,1H3

InChI key

DFOHHQRGDOQMKG-UHFFFAOYSA-N

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Description

  • Application: 4-Chloro-2-methylthiopyrimidine was used in the total synthesis of the marine alkaloid variolin B1 and 2-hydroxy-4-pyrimidinecarboxylic acid[1]. It was used in the synthesis of 2,4-disubstituted pyrimidines, a novel class of KDR kinase inhibitors[2]. It was used as building block in medicinal chemistry synthesis.[3][4]

SAFETY INFORMATION

Pictograms

GHS05

Signal Word

Danger

Hazard Statements

H314

Precautionary Statements

P280 - P303 + P361 + P353 - P304 + P340 + P310 - P305 + P351 + P338 - P363 - P405

Hazard Classifications

Skin Corr. 1B

WGK

WGK 3

Flash Point(F)

235.4 °F

Flash Point(C)

113 °C

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves