254606

(−)-Methyl (S)-2,2-dimethyl-1,3-dioxolane-4-carboxylate

96%

Manufacturer: Sigma Aldrich

CAS Number: 60456-21-5

Synonym(S): α,β-Isopropylidene-L-glyceric acid methyl ester, Methyl α,β-isopropylidene-L-glycerate, Methyl 2,3-O-isopropylidene-L-glycerate

Select a Size

Pack Size SKU Availability Price
5 G 254606-5-G In Stock ₹ 16,280.80

254606 - 5 G

₹ 16,280.80

In Stock

Quantity

1

Base Price: ₹ 16,280.80

GST (18%): ₹ 2,930.544

Total Price: ₹ 19,211.344

Quality Level

200

Assay

96%

form

liquid

optical activity

[α]20/D −8.5°, c = 1.5 in acetone

optical purity

ee: ≥96.0% (GLC)

refractive index

n20/D 1.425 (lit.)

bp

84-86 °C/15 mmHg (lit.)

density

1.106 g/mL at 25 °C (lit.)

SMILES string

COC(=O)[C@@H]1COC(C)(C)O1

InChI

1S/C7H12O4/c1-7(2)10-4-5(11-7)6(8)9-3/h5H,4H2,1-3H3/t5-/m0/s1

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Description

  • Application: (−)-Methyl (S)-2,2-dimethyl-1,3-dioxolane-4-carboxylate can be used:As a chiral building block to make the key tetrahydrofuran subunit of (−)-gymnodimine, a marine algal toxin.[1]To prepare an enedione by reacting with dimethyl methylphosphonate, BuLi, and phenylglyoxal, which in turn is used to synthesize cyclopentenone derivatives.[2]As a starting material for the preparation of (S)-4,5-dihydroxy-2,3-pentanedione (DPD), a precursor for autoinducer (AI)-2 in bacteria.[3]

SAFETY INFORMATION

WGK

WGK 3

Flash Point(F)

closed cup

Flash Point(C)

closed cup

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves