761524
Dibenzocyclooctyne-N-hydroxysuccinimidyl ester
for Copper-free Click Chemistry
Manufacturer: Sigma Aldrich
Synonym(S): DBCO-NHS ester, DBCO-SE
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| 5 MG | 761524-5-MG | In Stock | ₹ 7,783.18 |
| 50 MG | 761524-50-MG | In Stock | ₹ 29,444.00 |
761524 - 5 MG
In Stock
Quantity
1
Base Price: ₹ 7,783.18
GST (18%): ₹ 1,400.972
Total Price: ₹ 9,184.152
Quality Level
100
form
solid
reaction suitability
reaction type: click chemistryreagent type: cross-linking reagent
mp
149-157 (decomposition)
functional group
NHS ester
storage temp.
−20°C
SMILES string
O=C(CCC(ON(C(CC1)=O)C1=O)=O)N2CC3=C(C=CC=C3)C#CC4=C2C=CC=C4
InChI
1S/C23H18N2O5/c26-20(13-14-23(29)30-25-21(27)11-12-22(25)28)24-15-18-7-2-1-5-16(18)9-10-17-6-3-4-8-19(17)24/h1-8H,11-15H2
InChI key
XCEBOJWFQSQZKR-UHFFFAOYSA-N
Related Products
Description
- General description: DBCO-NHS ester is commonly used in bioconjugation. It consists of an NHS ester that reacts with primary amines on biomolecules and an alkyne group that allows for a specific reaction with molecules containing azides. This reaction is carried out through a copper-free click chemistry process called strain-promoted alkyne-azide cycloaddition.[1]
- Application: Dibenzocyclooctyne-N-hydroxysuccinimidyl ester is commonly used:In the modification and labeling of biomolecules such as antibodies and streptavidin by introducing DBCO groups onto their surfaces[2] As a cross linker to conjugate peptide antigens onto the surface of poly(lactic-co-glycolic acid) (PLGA) nanoparticles[3]
SAFETY INFORMATION
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable