790443

TCO-PEG3-maleimide

Manufacturer: Sigma Aldrich

Synonym(S): trans-Cyclooctene-maleimide

Select a Size

Pack Size SKU Availability Price
5 MG 790443-5-MG In Stock ₹ 17,731.35
25 MG 790443-25-MG In Stock ₹ 44,285.08

790443 - 5 MG

₹ 17,731.35

In Stock

Quantity

1

Base Price: ₹ 17,731.35

GST (18%): ₹ 3,191.643

Total Price: ₹ 20,922.993

form

liquid

Quality Level

100

reaction suitability

reaction type: click chemistryreagent type: linker

functional group

maleimide

storage temp.

−20°C

SMILES string

O=C(NCCCOCCOCCOCCCNC(CCN1C(C=CC1=O)=O)=O)OC2CCC/C=C/CC2

InChI

1S/C26H41N3O8/c30-23(12-15-29-24(31)10-11-25(29)32)27-13-6-16-34-18-20-36-21-19-35-17-7-14-28-26(33)37-22-8-4-2-1-3-5-9-22/h1-2,10-11,22H,3-9,12-21H2,(H,27,30)(H,28,33)/b2-1+

InChI key

BJZRPWAVCDJCTC-OWOJBTEDSA-N

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Description

  • Biochem/physiol Actions: Maleimide (thiol reactive) functionalized trans-cyclooctene derivative for incorporation of the cyclooctene moiety into thiol containing compounds or biomolecules. Trans-cyclooctenes are useful in strain-promoted copper-free click chemistry cycloaddition reactions with 1; 2; 4; 5-tetrazines. This cyclooctene will react with tetrazine functionalized compounds or biomolecules without the need for a catalyst to result in a stable covalent linkage. The 4+2 inverse electron demand Diels-Alder cycloaddition between trans-cyclooctene and tetrazines is the fastest biologically compatible ligation technology reported and has had many applications in biological labeling and imaging. The PEG spacer allows for increased water solubility; less aggregation and an increased distance between the thiol to be modified and the reactive alkene.

SAFETY INFORMATION

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable