902551

BocNH-PEG4-acid

Manufacturer: Sigma Aldrich

CAS Number: 876345-13-0

Synonym(S): 2,2-Dimethyl-4-oxo-3,8,11,14,17-pentaoxa-5-azanonadecan-19-oic acid, Boc-NH-PEG4-CH2COOH

Select a Size

Pack Size SKU Availability Price
250 MG 902551-250-MG In Stock ₹ 22,440.23
1 G 902551-1-G In Stock ₹ 73,198.65

902551 - 250 MG

₹ 22,440.23

In Stock

Quantity

1

Base Price: ₹ 22,440.23

GST (18%): ₹ 4,039.241

Total Price: ₹ 26,479.471

form

liquid

reaction suitability

reaction type: Pegylationsreagent type: cross-linking reagent

refractive index

n/D 1.4641

density

1.1395 g/mL

functional group

Bocaminecarboxylic acid

storage temp.

−20°C

SMILES string

OC(COCCOCCOCCOCCNC(OC(C)(C)C)=O)=O

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Description

  • Application: This heterobifunctional, PEGylated crosslinker features a carboxylic acid at one end and Boc-protected amino group at the other, which can be deprotected with mildly acidic conditions. The hydrophilic PEG linker facilitates solubility in biological applications. BocNH-PEG4-acid can be used for bioconjugation or as a building block for synthesis of small molecules, conjugates of small molecules and/or biomolecules, or other tool compounds for chemical biology and medicinal chemistry that require ligation. Examples of applications include its synthetic incorporation into antibody-drug conjugates or proteolysis-targeting chimeras (PROTAC® molecules) for targeted protein degradationTechnology Spotlight: Degrader Building Blocks for Targeted Protein Degradation
  • Other Notes: A Hexylchloride-Based Catch-and-Release System for Chemical Proteomic ApplicationsA Biocompatible Condensation Reaction for the Labeling of Terminal Cysteine Residues on Proteins
  • Legal Information: PROTAC is a registered trademark of Arvinas Operations, Inc., and is used under license

SAFETY INFORMATION

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable