902586
Hydroxy-PEG4-t-butyl ester
Manufacturer: Sigma Aldrich
CAS Number: 518044-32-1
Synonym(S): tert-Butyl-1-hydroxy-3,6,9,12-tetraoxapentadecan-15-oate, HO-PEG4-CO-OtBu
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| 1 G | 902586-1-G | In Stock | ₹ 24,161.40 |
902586 - 1 G
In Stock
Quantity
1
Base Price: ₹ 24,161.40
GST (18%): ₹ 4,349.052
Total Price: ₹ 28,510.452
Assay
≥95%
form
liquid
reaction suitability
reagent type: cross-linking reagent
refractive index
n/D 1.4492
density
1.04746 g/mL
functional group
esterhydroxyl
storage temp.
2-8°C
SMILES string
O=C(OC(C)(C)C)CCOCCOCCOCCOCCO
InChI
1S/C15H30O7/c1-15(2,3)22-14(17)4-6-18-8-10-20-12-13-21-11-9-19-7-5-16/h16H,4-13H2,1-3H3
InChI key
FJRDXEGYAVAMLB-UHFFFAOYSA-N
Other Options
| Image | Product Name | Manufacturer | Price Range | |
|---|---|---|---|---|
 | Sigma Aldrich Fine Chemicals Biosciences Hydroxy-PEG4-t-butyl ester | 518044-32-1 | 1G | -- | ₹ 29,556.70 | |
| | Hydroxy-PEG-5-t-butyl ester | -- | ₹ 342.24 - ₹ 82,993.20 | |
| | Hydroxy-PEG4-(CH2)2-Boc | -- | ₹ 1,197.84 - ₹ 18,395.40 | |
| | 518044-32-1 | t-Butyl 3-Hydroxy(PEG4)propoinate | -- | ₹ 342.24 - ₹ 64,170.00 |
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Description
- Application: This heterobifunctional, PEGylated crosslinker features a hydroxyl group at one end and t-butyl-protected carboxylic acid at the other, which can be deprotected with acidic conditions. The hydrophillic PEG linker facilitates solubility in biological applications. Hydroxy-PEG4-t-butyl ester can be used for bioconjugation or as a building block for synthesis of small molecules, conjugates of small molecules and/or biomolecules, or other tool compounds for chemical biology and medicinal chemistry that require ligation. Examples of applications include its synthetic incorporation into antibody-drug conjugates or proteolysis-targeting chimeras (PROTAC® molecules) for targeted protein degradation.
- Other Notes: Recruiting cytotoxic T cells to folate-receptor-positive cancer cellsSyntheses and characterizations of novel pyrrolocoumarin probes for SNAP-tag labeling technologyHigh density orthogonal surface immobilization via photoactivated copper-free click chemistry
- Legal Information: PROTAC is a registered trademark of Arvinas Operations, Inc., and is used under license
SAFETY INFORMATION
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable