Description

• General description: Phenylmagnesium bromide solution contains 3M phenylmagnesium bromide in diethyl ether. It can act as a strong acid and Lewis acid. It can undergo addition reaction with many unsaturated functional groups. The phenyl group can displace halide from other organic compounds.[1] Phenylmagnesium bromide is a Grignard reagent. Reaction of β-cyclohexanedione (dihydroresorcinol) with phenylmagnesium bromide has been investigated.[2]
• Application: Phenylmagnesium bromide was used for the synthesis of end-functionalized regioregular poly(3-alkylthiophene)s.[3] It was also used for the monoalkylation of aliphatic primary amine to generate secondary amines by the Grignard reaction of 1-[(alkylamino) methyl] benzotriazoles.[4] It may be used for synthesis of the following: 1,3,3-trimethyl-6-phenyl-2-oxabicyclo[2.2.2]octan-6-ol[5] 6-benzyl-1,3,3-trimethyl-2-oxabicyclo[2.2.2]octan-6-ol[5] (3-(2-Dithiobenzoatepropionyl)propyl)dimethylmethoxysilane, reversible addition-fragmentation chain transfer polymerization (RAFT)-silane agent[6] series of o-substituted benzophenones[7]
• Packaging: View returnable container options.
• Other Notes: Storage below 25°C may cause formation of crystalline magnesium salts. Moving container to a warm location and occasional gentle swirling should redissolve the solid