384410

Chlorotrimethylsilane solution

1.0 M in THF

Manufacturer: Sigma Aldrich

CAS Number: 75-77-4

Synonym(S): Trimethylchlorosilane

Select a Size

Pack Size SKU Availability Price
100 ML 384410-100-ML In Stock ₹ 3,850.00

384410 - 100 ML

₹ 3,850.00

In Stock

Quantity

1

Base Price: ₹ 3,850.00

GST (18%): ₹ 693.00

Total Price: ₹ 4,543.00

form

liquid

Quality Level

100

concentration

1.0 M in THF

density

0.88 g/mL at 25 °C

SMILES string

C[Si](C)(C)Cl

InChI

1S/C3H9ClSi/c1-5(2,3)4/h1-3H3

InChI key

IJOOHPMOJXWVHK-UHFFFAOYSA-N

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Description

  • General description: Chlorotrimethylsilane (TMSCl) is a silylating agent employed in the silylation of alcohols, amines, carboxylic acids, thiols, and other functional groups. Silyl group serves as a protecting group for these original functional groups.[1]
  • Application: Chlorotrimethylsilane (TMSCl) can be used as a reagent: To synthesize allenylsilane via carbolithiation of conjugated enynes with aryllithium.[1] In the reductive coupling of aldehydes and ketones to produce corresponding 1,2 diols in the presence of zirconocene dichloride and magnesium.[2] To prepare 4,4′-bis(trimethylsilyl)bicyclohexyl-2,2′-diene from 1,3-cyclohexadiene by reductive disilylation reaction.[3]

SAFETY INFORMATION

Pictograms

GHS02,GHS08,GHS05,GHS07

Signal Word

Danger

Hazard Statements

H225,H302,H314,H335,H351

Precautionary Statements

P201 - P210 - P233 - P261 - P280 - P370 + P378

Hazard Classifications

Acute Tox. 4 Oral - Carc. 2 - Flam. Liq. 2 - Skin Corr. 1A - STOT SE 3

Target Organs

Respiratory system

Supplementary Hazards

EUH014,EUH019

WGK

WGK 1

Flash Point(F)

-4.0 °F

Flash Point(C)

-20 °C

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves