758035

Jones reagent

Manufacturer: Sigma Aldrich

CAS Number: 65272-70-0

Synonym(S): Jone′s reagent, Chromium trioxide solution in sulfuric acid, Sulfuric acid-chromium trioxide mixture

Select a Size

Pack Size SKU Availability Price
25 ML 758035-25-ML In Stock ₹ 11,236.35
100 ML 758035-100-ML In Stock ₹ 28,437.28

758035 - 25 ML

₹ 11,236.35

In Stock

Quantity

1

Base Price: ₹ 11,236.35

GST (18%): ₹ 2,022.543

Total Price: ₹ 13,258.893

form

liquid

Quality Level

100

composition

2 M CrO3 in aqueous H2SO4

reaction suitability

core: chromiumreagent type: catalystreagent type: oxidant

density

1.298 g/mL at 25 °C

SMILES string

O=[Cr](=O)=O.OS(O)(=O)=O

InChI

1S/Cr.H2O4S.3O/c;1-5(2,3)4;;;/h;(H2,1,2,3,4);;;

InChI key

HNPXHFOTGAXAJY-UHFFFAOYSA-N

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Description

  • General description: Jones reagent is a solution of chromium trioxide in aqueous sulfuric acid. Using acetone as a reaction solvent, the reagent is usually used for the oxidation of primary and secondary alcohols to carboxylic acids and ketones, respectively.The oxidation is very rapid and exothermic. The reagent tolerates a variety of functionalities, such as, for example, unsaturated bonds, which are rarely oxidized.For a comprehensive review of chromium-based reagents, see "Oxidation of Alcohols to Aldehydes and Ketones" by Tojo and Fernández, Springer Berlin, 2006, 1-97.
  • Application: Jones reagent can be used:In the oxidative cleavage of various alkenes into carboxylic acids and ketones using a catalytic amount of osmium tetroxide.[1]To prepare symmetrical binaphthols by oxidative dehydrodimerization of substituted naphthols.[2]To synthesize acyl-naphthols and substituted isocoumarins from 2-(4-hydroxy-but-1-ynyl)benzaldehydes.[3]

SAFETY INFORMATION

Pictograms

GHS03,GHS06,GHS08,GHS05,GHS09

Signal Word

Danger

Hazard Statements

H271,H290,H301,H312,H314,H317,H330,H334,H335,H340,H350,H361f,H372,H410

Precautionary Statements

P210 - P273 - P280 - P303 + P361 + P353 - P304 + P340 + P310 - P305 + P351 + P338

Hazard Classifications

Acute Tox. 2 Inhalation - Acute Tox. 3 Oral - Acute Tox. 4 Dermal - Aquatic Acute 1 - Aquatic Chronic 1 - Carc. 1A - Eye Dam. 1 - Met. Corr. 1 - Muta. 1B - Ox. Liq. 1 - Repr. 2 - Resp. Sens. 1 - Skin Corr. 1A - Skin Sens. 1 - STOT RE 1 Inhalation - STOT SE 3

Target Organs

Respiratory system

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable