C4706
Tris(2-carboxyethyl)phosphine hydrochloride
powder
Manufacturer: Sigma Aldrich
CAS Number: 51805-45-9
Synonym(S): TCEP
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| 2 G | C4706-2-G | In Stock | ₹ 22,650.00 |
| 10 G | C4706-10-G | In Stock | ₹ 82,640.00 |
| 50 G | C4706-50-G | In Stock | ₹ 3,82,923.55 |
C4706 - 2 G
In Stock
Quantity
1
Base Price: ₹ 22,650.00
GST (18%): ₹ 4,077.00
Total Price: ₹ 26,727.00
description
Protect from moisture
Quality Level
300
form
powder
reaction suitability
reagent type: reductant
color
white
solubility
H2O: 50 mg/mL
storage temp.
2-8°C
SMILES string
Cl[H].OC(=O)CCP(CCC(O)=O)CCC(O)=O
InChI
1S/C9H15O6P.ClH/c10-7(11)1-4-16(5-2-8(12)13)6-3-9(14)15;/h1-6H2,(H,10,11)(H,12,13)(H,14,15);1H
InChI key
PBVAJRFEEOIAGW-UHFFFAOYSA-N
Other Options
Related Products
Description
- General description: Tris(2-carboxyethyl)phosphine hydrochloride (TCEP.HCl) is a non-volatile solid. It is a strong reducing agent.1[1] It can be synthesized by the acid hydrolysis of tris(2-cyanoethyl)phosphine in refluxing aqueous HCl.1[1] It has various biological applications such as in vitro and in vivo reduction of disulfide bonds in various peptides and proteins. TCEP is a useful chelating agent for various heavy metal ions as Zn(II), Cd(II), Pb(II), and Ni(II).[2]
- Application: Tris(2-carboxyethyl)phosphine hydrochloride (TCEP. HCl) can be used:As a reducing agent for the reduction of sulfoxides, sulfonyl chlorides, N-oxides, and azides. It can also be used in azide-alkyne cycloaddition reaction in the presence of a copper catalyst.[3]To reduce disulfide bonds in various proteins.[3]As a reagent for the selective reduction of disulfides in water.[1]To remove ruthenium-derived metathesis catalysts via aqueous washing of a crude reaction mixture when it is basified.[4][5]As a reducing agent for the reduction of various alkyl disulfides such as trans-4,5-dihydroxy-1,2-dithiane.[1]
- Caution: Storage conditions:protect from moisture.
SAFETY INFORMATION
Pictograms
Signal Word
Danger
Hazard Statements
Precautionary Statements
P260 - P280 - P303 + P361 + P353 - P304 + P340 + P310 - P305 + P351 + P338 - P363
Hazard Classifications
Eye Dam. 1 - Skin Corr. 1B
WGK
WGK 1
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves