4527528
Thermo Scientific™ MethElute™ Reagent (TMPAH)
For accurate, sensitive on-column methylation use Thermo Scientific™ MethElute™ Reagent (TMPAH).
Manufacturer: Fischer Scientific
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Storage
Room Temperature
Hazards
Flammable, Toxic
Standard Concentration
0.2 M
For Use With
GC
Standard Components
Trimethylanilinium hydroxide in Methanol
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Description
- For accurate, sensitive, on-column methylation and detection by GC analysis use Thermo Scientific™ MethElute™ Reagent (TMPAH)
- It is ideally suited for the quantitative methylation and detection of barbiturates, sedatives, xanthine bases, phenolic alkaloids, and phenytoin, giving a single quantitative peak for each substance
- When the reagent is heated with drug-containing extracts, serum, or urine the drugs containing reactive amino, hydroxyl, and carboxyl functions will be methylated at the reactive sites
- Performance Characteristics Accuracy comparable or better than the UV/TLC method (GC is superior to UV/TLC when phenobarbitol and phenytoin present) High precision, with coefficient of variation of 5% or less High sensitivity; barbiturates deteced down to 0.2 mg/dL