4673269
Cytiva MabSelect™ Chromatography Media
Protein A affinity medium designed for capturing MAbs from large sample volumes
Manufacturer: Fischer Scientific
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For Use With (Application)
For Industrial AppliCatIons and Well-Established in Approved Processes
Binding Capacity
30 mg Human lgG/mL (at 2.4 min. residence time)
Flow Rate
<500 cm/Hoμr
Height (English) Bed
7.87 in.
Includes
Certificate of Analysis
Matrix
Highly Cross-Linked Agarose
Ligand Type
Recombinant Protein A (E. coli)
Storage Requirements
2°C to 8°C
Product Type
MabSelect Media
Particle Size
85 μm
Height (Metric) Bed
20 cm
Max. Pressure
<200 kPa
pH Range
3 to 10
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Description
- High-flow agarose matrix allows for high flow velocities at production scale BioProcess medium supported for industrial applications and well-established in approved processes Low non-specific binding resulting in low levels of impurities in the product eluate pool Oriented coupling of ligand and optimized matrix gives high dynamic binding capacity Based on highly cross-linked agarose matrix with recombinant protein A ligand Ligand is engineered to favor oriented coupling and expressed in E
- coli and is free of components of mammalian origin Hydrophilic nature of the base matrix ensures low levels of non-specific Average particle size: 85μm (d50V) pH Stability cleaning-in-place (CIP): 2 to 12 pH Stability working range: 3 to 10 Ligand: recombinant protein A ( E.coli ) Matrix: highly cross-linked agarose Binding capacity/mL chromatography medium: ∽30mg human lgG/mL at 2.4 min
- residence time Pressure/Flow specification: <500cm/hr., <200 kPa, BPG 300, bed height 20cm