35-715-0R
Tocris Bioscience™ SB 657510
Manufacturer: Tocris Bioscience™
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Purity
>98%
Product Type
SB 657510
Inhibitors
SB 657510
Quantity
50 mg
Molecular Weight (g/mol)
505.81
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Description
- Selective urotensin-II (UT) receptor antagonist (K i values are 61, 17, 30, 65 and 56 nM at human, monkey, cat, rat and mouse receptors respectively)
- Inhibits U-II-induced intracellular Ca 2+ mobilization (IC 50 = 180 nM) and antagonizes the contractile action of U-II in isolated mammalian arteries and aortae (EC 50 = 50 - 189 nM).