37-125-0R
Tocris Bioscience™ NU 7441
Manufacturer: Fischer Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 37-125-0R-Each-of-1 | In Stock | ₹ 1,20,211.80 |
37-125-0R - Each of 1
In Stock
Quantity
1
Base Price: ₹ 1,20,211.80
GST (18%): ₹ 21,638.124
Total Price: ₹ 1,41,849.924
Purity
>99%
Quantity
50 mg
Molecular Weight (g/mol)
413.49
Gene Alias
KU 57788
Product Type
NU 7441
Inhibitors
NU 7441
Related Products
Description
- Potent and selective DNA-PK inhibitor (IC50 = 14 nM)
- Selective for DNA-PK over a range of kinases including mTOR, PI 3-K, ATM and ATR
- Potentiates the effects of doxorubicin (Cat
- No
- 2252) and etoposide (Cat
- No
- 1226) in vitro and etoposide in vivo
- Also enhances CRISPR-Cas9-mediated homology-directed repair (HDR) efficiency 2 to 3-fold, and decreases nonhomologous end-joining (NHEJ) frequency ∽40%.