41-505-0
Tocris Bioscience™ Azidothymidine
Manufacturer: Tocris Bioscience™
CAS Number: 30516-87-1
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Purity
99%
CAS
30516-87-1
Quantity
50 mg
Molecular Weight (g/mol)
M.W. (Observed): 267.24
Molecular Formula
3 '-Azido-3 '-deoxythymidine
Content And Storage
-20°C
Product Type
Azidothymidine
Inhibitors
Azidothymidine
Other Options
Related Products
Description
- Selective reverse transcriptase inhibitor
- Exhibits 100-fold selectivity for HIV reverse transcriptase over DNA polymerase α
- Suppresses HIV-1 replication and enhances cell viability in HIV-1 infected T cells
- Attenuates growth of multiple myeloma (MM) cells in vitro and reduces growth of MM tumor xenografts in mice
- Increases differentiation iPSCs into cortical neurons and reduces the over-proliferation of neural precursors
- Orally bioavailable and brain penetrant
- Antiretroviral agent
- Also decreases CRISPR-mediated homology directed repair (HDR) efficiency.