49-725-0R
Tocris Bioscience™ JIB 04
Manufacturer: Fischer Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 49-725-0R-Each-of-1 | In Stock | ₹ 90,009.12 |
49-725-0R - Each of 1
In Stock
Quantity
1
Base Price: ₹ 90,009.12
GST (18%): ₹ 16,201.642
Total Price: ₹ 1,06,210.762
Purity
>99%
Product Type
JIB 04
Inhibitors
JIB 04
Quantity
50 mg
Molecular Weight (g/mol)
308.76
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Description
- Pan Jumonji histone demethylase inhibitor (IC50 values are 230, 340, 435, 445, 855 and 1100 nM for JARID1A, JMJD2E, JMJD2B, JMJD2A, JMJD3 and JMJD2C respectively)
- Exhibits negligible activity at PHD2 and TET1
- Selectively blocks cancer cell growth in vitro and diminishes tumor growth in H358 and A549 mouse xenograft models in vivo
- Prolongs survival in a mouse model of breast cancer.