50-505-0R

Tocris Bioscience™ CASIN

Manufacturer: Fischer Scientific

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Purity

>98%

Product Type

CASIN

Inhibitors

CASIN

Quantity

50 mg

Molecular Weight (g/mol)

306.4

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Description

  • Cdc42 GTPase inhibitor (IC50 = 2 μM)
  • Reduces active levels of Cdc42 in aged hematopoietic stem cells (HSCs) to that in young HSCs
  • Reverses the aging-related and polarity phenotype of aged HSCs to that of young HSCs in vivo
  • Increases histone H4K16 acetylation in aged HSCs.