5545665

Tocris Bioscience™ A 366

Potent and selective G9a/GLP inhibitor

Manufacturer: Fischer Scientific

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Purity

>98%

Product Type

A 366

Molecular Weight (g/mol)

329.44

Inhibitors

A 366

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Description

  • Potent and selective G9a/GLP histone lysine methyltransferase inhibitor (IC50 = 3.3 nM)
  • Exhibits >1000-fold selectivity for G9a/GLP over 21 other methyltransferases
  • Decreases levels of lysine 9 dimethylation on histone H3 (H3K9Me2) in PC3 cells.