5545716
Tocris Bioscience™ BMS 195614
Selective RARα antagonist
Manufacturer: Fischer Scientific
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Purity
>98%
Product Type
BMS 195614
Inhibitors
BMS 195614
Gene Alias
BMS614
Molecular Weight (g/mol)
448.51
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Description
- Neutral retinoic acid receptor (RAR) α-selective antagonist (Ki = 2.5 nM)
- Displays no significant effect on nuclear receptor corepressor (NCoR) binding; moderately decreases SMRT binding to RAR
- Antagonizes agonist-induced coactivator (CoA) recruitment.