5545751
Tocris Bioscience™ Cladribine
Deoxyadenosine analog; pro-apoptotic
Manufacturer: Fischer Scientific
The price for this product is unavailable. Please request a quote
Purity
>99%
Product Type
Cladribine
Molecular Weight (g/mol)
285.69
Inhibitors
Cladribine
Related Products
Description
- Adenosine deaminase (ADA)-resistant analog of deoxyadenosine
- Exhibits anti-leukemic activity; Inhibits cell growth of lymphoid and myeloid neoplasm (IC50 = 20 - 87 nM)
- Pro-apoptotic; induces DNA double-strand breaks
- Also inhibits ribonuclease reductase (IC50 = 0.11 - 0.28 μM)
- Displays activity in vitro and in vivo
- Orally bioavailable.