5545838
Tocris Bioscience™ J 147
Neuroprotective and neurotrophic compound; reduces Aβ40 and Aβ42 levels
Manufacturer: Fischer Scientific
The price for this product is unavailable. Please request a quote
Purity
>99%
Product Type
J 147
Molecular Weight (g/mol)
350.33
Inhibitors
J 147
Related Products
Description
- Potent neuroprotective and neurotrophic compound
- Protects against neurotoxicity in cortical neurons in vitro (EC50 = 25 - 200 nM)
- Reduces soluble Aβ40 and Aβ42 levels and increases BDNF levels in the hippocampus in vivo
- Enhances memory in wild type rats
- Prevents memory deficits and rescues cognitive deficits in young and aged transgenic Alzheimer's disease mice, respectively
- Orally active.