5545929
Tocris Bioscience™ NS 9283
Positive allosteric modulator of α4β2 nAChRs
Manufacturer: Fischer Scientific
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Purity
>99%
Product Type
NS 9283
Molecular Weight (g/mol)
248.24
Inhibitors
NS 9283
Related Products
Description
- Positive allosteric modulator of α4β2 receptor; increases the potency of Ach-evoked currents ∽60 fold without effecting the maximum efficacy (HEK293-hα4β2 cells)
- Reduces the rate of recovery from desensitization and slows the rate of deactivation
- Displays a synergistic effect on the Emax when given with NS206 at 3α:2β receptors.