5546010
Tocris Bioscience™ SB 297006
Potent and selective CCR3 antagonist
Manufacturer: Fischer Scientific
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Purity
>99%
Product Type
SB 297006
Molecular Weight (g/mol)
342.35
Inhibitors
SB 297006
Related Products
Description
- Potent and selective CCR3 antagonist (IC50 = 39 nM)
- Displays 250-fold selectivity for CCR3 over other chemokine receptors, including CXCR1, CXCR2, CCR1 and CCR7 (IC50 >27 μM)
- Inhibits calcium mobilization induced by MCP-4, eotaxin-2 and eotaxin in RBL-2H3 cells transfected with CCR3 (IC50 values are 80, 90 and 210 nM respectively).