Description

• General description: Hexamethyldisilane (HMDS) is a stable and effectivereagent for trimethylsilylation of hydrogen-labile substrates such as alcohols,amines, and carboxylic acids. It is commonly used for the protection of sensitivefunctional groups during chemical synthesis. Owing to its low cost, high vapor pressure, and safety, itis widely used as a precursor in chemical vapor deposition(CVD) reactions.
• Application: Hexamethyldisilane (HMDS) can be used:As a silylating agent in the trimethylsilylation of alcohols under nearly neutral reaction conditions.To control the molecular weights of polypeptides during ring-opening polymerization of α-amino acid N-carboxyanhydrides.To fabricate silicon carbonitride thin films by plasma-enhanced CVD.For specimen preparation for scanning electron microscopy and the preparation of trimethylsilyl ethers from hydroxy compounds.
• Features and Benefits: High chemicalstability and low molecular weightNontoxic andcost-effective reagentAmmonia is theonly byproduct generated during silylationSilylationreaction using HDMS is nearly neutral and does not need any precaution