G-Biosciences T4 UvsX DNA Recombinase

Description

• T4 UvsX DNA Recombinase forms a right-handed nucleoprotein complex on single ssDNA called the presynaptic filament that can search for homology in duplex DNA and pair the recombining DNA molecules to form a DNA joint molecule
• This process is aided by ssDNA binding proteins and recombination mediators
• The filament is then elongated by DNA polymerase with the newly synthesized strand displacing the old strand
• The newly synthesized duplex DNA can then act as a template for the next cycle to achieve exponential amplification of dsDNA