52-885-0
Tocris Bioscience™ R 268712
Manufacturer: Fischer Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 52-885-0-Each-of-1 | In Stock | ₹ 1,39,633.92 |
52-885-0 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 1,39,633.92
GST (18%): ₹ 25,134.106
Total Price: ₹ 1,64,768.026
Purity
>98%
Product Type
R 268712
Inhibitors
R 268712
Quantity
50 mg
Molecular Weight (g/mol)
363.39
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Description
- Potent and selective inhibitor of the TGF-β type I receptor/ALK5 (IC50 = 2.5 nM)
- Exhibits ∽5000-fold selectivity over p38 MAPK
- Suppresses development of renal fibrosis in a unilateral ureteral obstruction model
- Also reduces proteinuria, glomerulosclerosis and improves renal function in an anti-Thy1 glomerulonephritis model
- Orally bioavailable.