5546166
Tocris Bioscience™ M8 B hydrochloride
Potent and selective TRPM8 channel blocker
Manufacturer: Fischer Scientific
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Purity
>99%
Product Type
M8 B hydrochloride
Molecular Weight (g/mol)
432.96
Inhibitors
M8 B hydrochloride
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Description
- Potent and selective TRPM8 channel blocker
- Blocks cold- and icilin -induced TRPM8 activation in vitro (IC50 values are 7.8 and 26.9 nM respectively)
- Exhibits no effect at other TRP channels (IC50 > 20 μM)
- Reduces body temperature in vivo .