5546212

Tocris Bioscience™ WZ 4003

Potent and selective NUAK1/2 inhibitor

Manufacturer: Fischer Scientific

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Purity

>98%

Product Type

WZ 4003

Molecular Weight (g/mol)

496.99

Inhibitors

WZ 4003

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Description

  • Potent and selective NUAK1/2 inhibitor (IC50 values are 20 and 100 nM respectively)
  • Exhibits no significant inhibition against a panel of 139 kinases, including ten AMPK family members
  • Inhibits NUAK1-mediated MYPT1 phosphorylation
  • Also inhibits cell proliferation in U2OS cells.