123447

3,4-Dihydroxy-3-cyclobutene-1,2-dione

≥99.0% (HPLC)

Manufacturer: Sigma Aldrich

CAS Number: 2892-51-5

Synonym(S): Squaric acid

Select a Size

Pack Size SKU Availability Price
5 G 123447-5-G In Stock ₹ 7,674.93
25 G 123447-25-G In Stock ₹ 16,248.33
100 G 123447-100-G In Stock ₹ 52,977.55

123447 - 5 G

₹ 7,674.93

In Stock

Quantity

1

Base Price: ₹ 7,674.93

GST (18%): ₹ 1,381.487

Total Price: ₹ 9,056.417

Quality Level

200

Assay

≥99.0% (HPLC)

form

solid

mp

>300 °C (lit.)

SMILES string

OC1=C(O)C(=O)C1=O

InChI

1S/C4H2O4/c5-1-2(6)4(8)3(1)7/h5-6H

InChI key

PWEBUXCTKOWPCW-UHFFFAOYSA-N

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Description

  • General description: 3,4-dihydroxy-3-cyclobutene-1,2 dione, commonly known as squaric acid, is widely used in bioorganic and medicinal chemistry. It is an inhibitor of glyoxylase, semiqauric acid, pyruvate dehrogenase, and transketolase. It is used as a replacement for phosphate in a peptide-based ligand for an SH2 domain. Its derivatives are high-affinity ligands for excitatory amino acid receptors.[1] These derivatives are also used as dyes for fluorescence detection of small biological molecules.[2]
  • Application: 3,4-Dihydroxy-3-cyclobutene-1,2-dione can be used:In fluorescence detection in immunoassays, hybridization assays, enzymatic reactions, and other analytical procedures.[2]To form diffraction quality crystals.[3] To synthesize a squarate dianion, which is used as a building block to create uncharged polymeric networks. These ordered structures are used in catalysis, nonlinear optics, electrical conductivity, molecular recognition, and molecular sieves.[4]

SAFETY INFORMATION

Pictograms

GHS05

Signal Word

Danger

Hazard Statements

H314

Precautionary Statements

P260 - P280 - P303 + P361 + P353 - P304 + P340 + P310 - P305 + P351 + P338 - P363

Hazard Classifications

Eye Dam. 1 - Skin Corr. 1B

WGK

WGK 3

Flash Point(F)

374.0 °F

Flash Point(C)

190 °C

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves