926248
Redox Responsive Poly(ethylene glycol)-block-poly(lactide-alt-glycolide)
PEG average Mn 5000, PLGA Mn 15000
Manufacturer: Sigma Aldrich
Synonym(S): Drug release, PEG-PLGA with disulfide linkage, PEG-SS-PLGA, Stimuli-responsive
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| 1 G | 926248-1-G | In Stock | ₹ 65,360.00 |
926248 - 1 G
In Stock
Quantity
1
Base Price: ₹ 65,360.00
GST (18%): ₹ 11,764.80
Total Price: ₹ 77,124.80
form
powder, chunks or granules
Quality Level
100
mol wt
PEG average Mn 5000PLGA Mn 15000
storage temp.
2-8°C
SMILES string
O=C(C(C)OC(CO[H])=O)OCCSSCCOC(OCCOCCOC)=O
Related Products
Description
- Application: PEG-SS-PLGA is a redox responsive, biocompatible, amphiphilic block copolymer composed of a hydrophilic PEG block and a hydrophobic poly(lactide-alternative-glycolide) (PLGA) block, with a reducible disulfide linkage between blocks. This polymer can be fabricated into Glutathione (GSH) responsive nanoparticles which can be used as an intracellular drug delivery system. Different from common Poly(lactide-co-glycolide) (PLGA) polymer, the lactic and glycolic units in Poly(lactide-alt-glycolide) block alternate in sequence in the polymer chain, and the molar ratio of lactic to glycolic units in the polymer is exactly 1:1.Poly(lactide-alt-glycolide) exhibits excellent solubility in common organic solvents, such as acetonitrile, acetone, dioxane, DCM, and THF, providing great convenience for drug delivery researches and applications.
SAFETY INFORMATION
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable