D8783
7-Deaza-2′-deoxyguanosine 5′-triphosphate lithium salt
10 mM in H2O
Manufacturer: Sigma Aldrich
CAS Number: 101515-08-6
Synonym(S): −N7-dGTP, 7-Deaza-dGTP
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| 0.5 μMOL | D8783-0.5-μMOL | In Stock | ₹ 14,418.90 |
D8783 - 0.5 μMOL
In Stock
Quantity
1
Base Price: ₹ 14,418.90
GST (18%): ₹ 2,595.402
Total Price: ₹ 17,014.302
biological source
Porcine musclerabbit muscle
Quality Level
200
Assay
≥95% (HPLC)
form
liquid
concentration
10 mM in H2O
color
colorless
shipped in
dry ice
storage temp.
−20°C
SMILES string
NC1=NC(=O)c2ccn(C3CC(O)C(COP(O)(=O)OP(O)(=O)OP(O)(O)=O)O3)c2N1
InChI
1S/C11H17N4O13P3/c12-11-13-9-5(10(17)14-11)1-2-15(9)8-3-6(16)7(26-8)4-25-30(21,22)28-31(23,24)27-29(18,19)20/h1-2,6-8,16H,3-4H2,(H,21,22)(H,23,24)(H2,18,19,20)(H3,12,13,14,17)
Other Options
| Image | Product Name | Manufacturer | Price Range | |
|---|---|---|---|---|
 | Sigma Aldrich Fine Chemicals Biosciences 7-Deaza-2'-deoxyguanosine 5'-triphosphate lithium salt 10 mM in H2O | 101515-08-6 | MFCD00171614 | 0.5UMO | -- | ₹ 14,988.40 |
Related Products
Description
- Application: 7-Deaza-2′-deoxyguanosine 5′-triphosphate lithium salt has been used as a lysis agent to evaluate its efficiency on direct cell lysis, RNA stability, and compatibility with downstream reverse transcription quantitative real-time PCR during the analyzes of samples with small numbers of cells.[1]
- Biochem/physiol Actions: 7-Deaza-2′-deoxyguanosine 5′-triphosphate (7-deaza-dGTP) competes with natural substrate dGTP and blocks the telomerase activity. This nucleotide once incorporated into the telomere alters the secondary structure of the telomere making it difficult for telomerase to identify it for further telomere synthesis.[2] This dGTP analog pairs weakly with conventional bases to minimize DNA secondary structures, while being a good substrate for DNA polymerases. 7-deaza-dGTP in combination with dimethyl sulfoxide (DMSO) and betaine enhances the polymerase chain reaction (PCR) amplification of GC-rich DNA sequences.[3]
SAFETY INFORMATION
WGK
WGK 2
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable