TaqMan™ PGx Express Panel, 384-well plate

Description

• This TaqMan PGx (Pharmacogenomics) Express Panel is offered in pre-spotted 384-well plates, an efficient, easy-to-use format for pharmacogenomics applications
• The TaqMan PGx Express Panel contains 64 TaqMan DME and SNP genotyping assays per 384-well plate
• The assays were developed to detect polymorphisms in genes encoding drug metabolism enzymes (DMEs) and associated transport proteins
• This panel provides coverage of essential, commonly studied markers within CYP2D6, CYP2C9, CYP2C19, and other important DME and clinical research genes
• Each TaqMan Drug Metabolism and SNP genotyping assay in the panel contains two allele-specific probes and a primer pair to detect the specific SNP target
• Both the probes and primers uniquely align within the genome, enabling the TaqMan genotyping technology to provide superior specificity
• It is this specificity that allows these assays to detect targets residing in highly homologous gene families that may include pseudogenes
• TaqMan Drug Metabolism genotyping assays were developed using a high level of bioinformatics and wet-lab stringency
• All assays have passed performance tests involving 180 unique DNA samples from four different populations
• The plate is pre-formatted and inventoried, cost-effective, convenient, and easy-to-use, without the need for expensive robotics
• Results are reproducible and consistent across samples, studies, and labs—for the same data quality from plate-to-plate and lot-to-lot, even with different operators
• For fast delivery, all assays in this collection have been manufactured and placed into inventory and are ready to ship at ambient temperature.