M7824

Methotrexate

Manufacturer: SAFC

CAS Number: 59-05-2

Synonym(S): Methotrexate, (+)-Amethopterin, 4-Amino-10-methylfolic acid, 4-Amino-N10-methylpteroyl-L-glutamic acid, Antifolan, MTX, Methylaminopterin

Select a Size

Pack Size SKU Availability Price
1 G M7824-1-G In Stock ₹ 3,39,866.46
5 G M7824-5-G In Stock ₹ 14,68,403.46

M7824 - 1 G

₹ 3,39,866.46

In Stock

Quantity

1

Base Price: ₹ 3,39,866.46

GST (18%): ₹ 61,175.963

Total Price: ₹ 4,01,042.423

biological source

synthetic

Quality Level

400

form

powder

suitability

suitable for manufacturing use

storage temp.

−20°C

SMILES string

CN(Cc1cnc2nc(N)nc(N)c2n1)c3ccc(cc3)C(=O)N[C@@H](CCC(O)=O)C(O)=O

InChI

1S/C20H22N8O5/c1-28(9-11-8-23-17-15(24-11)16(21)26-20(22)27-17)12-4-2-10(3-5-12)18(31)25-13(19(32)33)6-7-14(29)30/h2-5,8,13H,6-7,9H2,1H3,(H,25,31)(H,29,30)(H,32,33)(H4,21,22,23,26,27)/t13-/m0/s1

InChI key

FBOZXECLQNJBKD-ZDUSSCGKSA-N

Gene Information

human ... DHFR(1719)

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Description

  • General description: Inhibits thymidylate synthetase, is a nonselective de novo purine synthesis inhibitor and has a significant toxicity profile including hepatotoxicity, pneumonitis and bone marrow suppression. Potent folic acid antagonist. Induces apoptosis in HL-60 human leukemia cells. Also useful as an anti-tumor agent.
  • Legal Information: SAFC is a registered trademark of Merck KGaA, Darmstadt, Germany

SAFETY INFORMATION

Pictograms

GHS06,GHS08

Signal Word

Danger

Hazard Statements

H301,H341,H360D,H372

Precautionary Statements

P202 - P260 - P264 - P280 - P301 + P310 - P405

Hazard Classifications

Acute Tox. 3 Oral - Muta. 2 - Repr. 1B - STOT RE 1

Target Organs

Liver,Bone marrow

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable