4530989

Thermo Scientific™ Pierce™ DSP, No-Weigh™ Format

Crosslink amines to amines with dithiobis succinimidyl propionate, composed of NHS-ester groups and disulfide-containing, 12.0A spacer arm and cleavable with reducing agents.

Manufacturer: Fischer Scientific

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Chemical Reactivity

Amine-Amine

Description

DSP

PEGylated

No

Content And Storage

Upon receipt store desiccated at 4°C.

Labeling Method

Chemical Labeling

Reactive Moiety

NHS Ester

Form

Powder

Format

Standard, Single-use, Premium-grade

Product Type

Crosslinker

Cleavable

By Thiols

Molecular Weight (g/mol)

404.42

Spacer Arm Length

12.0 Å

Cell Permeability

Yes

Crosslinker Type

Homobifunctional

Spacer

Medium (10 to 30 Å)

Solubility

DMF, DMSO

Water Soluble

No

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Description

  • Thermo Scientific™ Pierce DSP Crosslinker (Lomant's Reagent) is an amine-reactive crosslinker with NHS-ester reactive ends and a cleavable disulfide bond in its spacer arm
  • Highlights: Cleavable by reducing agents Membrane-permeable Acylate in aqueous or organic media within two minutes at room temperature Four- to five-hour half-life of ester at pH 7.0 Reactive groups: NHS ester (homobifunctional) Reactive toward: amino groups