4531007

Thermo Scientific™ DMP (dimethyl pimelimidate)

Crosslink amines to amines with dimethyl pimelimidate (CAS 58537-94-3); composed of imidoester groups and a membrane-permeable, 7-atom spacer arm.

Manufacturer: Fischer Scientific

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Chemical Reactivity

Amine-Amine

Description

DMP

PEGylated

No

Content And Storage

Upon receipt store desiccated at 4°C.

Shipping Condition

Ambient

Labeling Method

Chemical Labeling

Reactive Moiety

Imidoester

Form

Powder

Format

Standard

Product Type

Crosslinker

Cleavable

No

Molecular Weight (g/mol)

259.17

Spacer Arm Length

9.2 Å

Cell Permeability

Yes

Product Line

Pierce™

Crosslinker Type

Homobifunctional

Spacer

Short (<10 Å)

Solubility

Water

Water Soluble

Yes

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Description

  • Thermo Scientific™ Pierce DMP is dimethyl pimelimidate, a membrane-permeable crosslinker that contains an amine-reactive imidoester group at each end of a 7-atom spacer arm
  • Highlights: Water-soluble Rapid reaction with amines at alkaline pH values (pH 8-10) Amidine bond retains net charge character of protein Reversible at high pH values Reactive groups: imidoester (homobifunctional) Reactive toward: amino groups