7180382

Thermo Scientific™ Pierce™ SMCC

No-Weigh™ Format

Manufacturer: Fischer Scientific

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Chemical Reactivity

Amine-Sulfhydryl

Description

SMCC

PEGylated

No

Content And Storage

Upon receipt store desiccated at 4°C.

Shipping Condition

Ambient

Crosslinker Type

Heterobifunctional

Spacer

Short (<10 Å)

Solubility

DMF, DMSO

Water Soluble

No

Cleavable

By Thiols

Molecular Weight (g/mol)

334.32

Spacer Arm Length

8.3 Å

Cell Permeability

Yes

Labeling Method

Chemical Labeling

Reactive Moiety

Maleimide, NHS Ester

Form

Powder

Format

Standard, Single-use

Product Type

Crosslinker

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Description

  • Thermo Scientific™ Pierce SMCC is an amine-to-sulfhydryl crosslinker that contains NHS-ester and maleimide reactive groups at opposite ends of a medium-length cyclohexane-stabilized spacer arm (8.3 Ås)
  • Highlights: Cyclohexane bridge adds stability to the maleimide-reactive group; N-(4-carboxycyclohexylmethyl) maleimide groups are stable for 64 hours in 0.1 M sodium phosphate buffer, pH 7.0 at 4°C Ideal for coupling enzymes to antibodies Reactive groups: NHS-ester and maleimide Reactive toward: amino and sulfhydryl groups