K210
R&D Systems™ Human MDM2/S5a Ubiquitination Kit
Manufacturer: R&D Systems™
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Content And Storage
Store the unopened product at -70°C. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Do not use past expiration date.
Quantity
1 Kit
Gene Symbol
MDM2
Product Type
ACTFS, Angiocidin, ASF, HDM2, HDMX, Macropain, Mcb1, MDM2 oncogene, E3 ubiquitin protein ligase, PSMD4, pUB-R5, Rpn10 S5a
Gene ID (Entrez)
4193
Related Products
Description
- The RING-finger ubiquitin E3 ligase MDM2 (Murine Double Minute 2) is an important regulator of the tumor suppressor protein p53
- MDM2 ligase activity is at least partially responsible for the ubiquitination and subsequent proteasomal degradation of p53 and other proteins
- Ubiquitinated proteins can be used in downstream applications, or analyzed by Western blot using antibodies specific for the target protein