12-685-5100MG
MilliporeSigma™ Calbiochem™ Alendronate, Sodium Salt
Manufacturer: MilliporeSigma™
CAS Number: 121268-17-5
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 12-685-5100MG-Each-of-1 | In Stock | ₹ 22,280.68 |
12-685-5100MG - Each of 1
In Stock
Quantity
1
Base Price: ₹ 22,280.68
GST (18%): ₹ 4,010.522
Total Price: ₹ 26,291.202
Color
White
Target Proteins
Farnesyl diphosphate synthase
Molecular Formula
C4H12NNaO7P2·3H2O
Solubility
H2O
Form
Solid
Description
98% by titration
CAS
121268-17-5
Formula Weight
325.1g/mol
Content And Storage
Hygroscopic
Quantity
100 mg
Other Options
| Image | Product Name | Manufacturer | Price Range | |
|---|---|---|---|---|
 | Alendronate Sodium Pharmaceutical Secondary Standard, MilliporeSigma™ Supelco™ | -- | ₹ 14,433.97 | |
| | Sigma Aldrich Fine Chemicals Biosciences Alendronate sodium trihydrate >=97% (NMR), powder | 121268-17-5 | MFCD01748233 | 100MG | -- | ₹ 27,565.72 | |
| | Sigma Aldrich Fine Chemicals Biosciences Alendronate sodium United States Pharmacopeia (USP) Reference Standard | 121268-17-5 | MFCD01748233 | 200MG | -- | ₹ 45,791.71 | |
| | Sigma Aldrich Fine Chemicals Biosciences Sodium alendronate trihydrate European Pharmacopoeia (EP) Reference Standard | 121268-17-5 | MFCD01748233 | | -- | ₹ 16,036.51 | |
| | Alendronate Sodium | -- | ₹ 14,256.53 | |
| | Alendronate sodium | -- | ₹ 40,756.13 | |
| | Sodium alendronate trihydrate | -- | ₹ 14,072.50 | |
| | Sodium alendronate | -- | ₹ 21,401.03 | |
| | Alendronate (sodium hydrate) | -- | ₹ 427.80 - ₹ 38,929.80 | |
| | 121268-17-5 | sodium trihydrate hydrogen (4-amino-1-hydroxy-1-phosphonobutyl)phosphonate | -- | ₹ 427.80 - ₹ 3,935.76 |
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Description
- An amino-bisphosphonate that acts as a potent inhibitor of bone resorption and cartilage destruction
- Causes disruption of the ruffled border and actin cytoskeleton of osteoclasts and induces in vitro apoptosis of osteoclasts and macrophages by inhibiting farnesyl diphosphate synthase (IC 50 = 460 nM)
- Efficiently chelates metal ions and functions as a broad-spectrum MMP inhibitor (IC 50 ∽ 40 - 70μM)
- Also displays antimetastatic, anti-invasive and cell-adhesion-promoting properties (IC 50 ∽ 1 pM, in vitro invasion of prostate cancer cells).