32-476-125MG

MilliporeSigma™ Calbiochem™ Elastase Inhibitor V

Manufacturer: MilliporeSigma™

Select a Size

Pack Size SKU Availability Price
Each of 1 32-476-125MG-Each-of-1 In Stock ₹ 22,793.18

32-476-125MG - Each of 1

₹ 22,793.18

In Stock

Quantity

1

Base Price: ₹ 22,793.18

GST (18%): ₹ 4,102.772

Total Price: ₹ 26,895.952

Color

Off-white

Target Proteins

Elastase

Formula Weight

336.6g/mol

Content And Storage

Protect from Light, Protect from Moisture

Quantity

25 mg

Description

99% by HPLC

Molecular Formula

C14H7BrClNO2

Solubility

DMSO

Form

Solid

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Description

  • A benzoxazinone compound that acts as a potent inhibitor of human leukocyte elastase (IC 50 = 29.5nM), likely by covalently modifying active site serine
  • Shown to inhibit elastase secretion (IC 50 = 80.8nM), but not O 2 generation, in fLMP -stimulated primary human neutrophil cultures
  • Reported to reduce neutrophil infiltration in lung after hemorrhagic shock in rats in vivo (1mg/kg, i.v.).