38-219-05MG
MilliporeSigma™ Calbiochem™ Histone Lysine Methyltransferase Inhibitor
Manufacturer: MilliporeSigma™
CAS Number: 935693-62-2
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 38-219-05MG-Each-of-1 | In Stock | ₹ 24,076.58 |
38-219-05MG - Each of 1
In Stock
Quantity
1
Base Price: ₹ 24,076.58
GST (18%): ₹ 4,333.784
Total Price: ₹ 28,410.364
Color
Off-white
CAS
935693-62-2
Formula Weight
490.6g/mol
Content And Storage
Protect from light
Quantity
5 mg
Description
97% by HPLC
Molecular Formula
C28H38N6O2
Solubility
DMSO or EtOH
Form
Solid
Other Options
| Image | Product Name | Manufacturer | Price Range | |
|---|---|---|---|---|
 | Thermo Scientific™ BIX-01294, 95% | -- | ₹ 24,812.40 | |
| | Medchemexpress LLC HY-10587 10mg Medchemexpress, BIX-01294 CAS:935693-62-2 Purity:>98% | -- | ₹ 13,385.86 | |
| | Enzo Life Sciences BIX 01294 (2mg). CAS: 935693-62-2 | -- | ₹ 28,534.26 | |
| | 935693-62-2 | 4-Quinazolinamine, 2-(hexahydro-4-methyl-1H-1,4-diazepin-1-yl)-6,7-dimethoxy-N-[1-(phenylmethyl)-4-piperidinyl]- | -- | ₹ 855.60 - ₹ 31,913.88 |
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Description
- A cell-permeable diazepinyl-quinazolinamine, non-SAM (S-adenosylmethionine) analog-based HMTase (histone methyltransferase) inhibitor that selectively interferes with the G9a-catalyzed H3K9me2 (histone H3 Lys9 dimethylation) modification (IC 50 = 1.7μM) in a reversible manner
- It inhibits the GLP-catalyzed H3K9me3 only at much higher concentrations (IC 50 = 38μM) and exhibits little activity against H3 methylations catalyzed by other HMTases (PRMT1, SET7/9, ESET, SUV39H1)
- Shown to effectively synergize with Oct 3/4 and Klf 4 in inducing reprogramming of primary murine fetal NPCs (Neural Progenitor Cells) into iPS (induced Pluripotent Stem) cells without additional viral transduction of Sox2 and c- Myc .