44-428-21MG

MilliporeSigma™ Calbiochem™ MMP/TACE Substrate, FS-6

Manufacturer: MilliporeSigma™

Select a Size

Pack Size SKU Availability Price
Each of 1 44-428-21MG-Each-of-1 In Stock ₹ 26,049.60

44-428-21MG - Each of 1

₹ 26,049.60

In Stock

Quantity

1

Base Price: ₹ 26,049.60

GST (18%): ₹ 4,688.928

Total Price: ₹ 30,738.528

Formulation

Supplied as a trifluoroacetate salt.

Target Proteins

Broad-spectrum MMP and TACE substrate

Formula Weight

1221.3g/mol

Content And Storage

Hygroscopic, Protect from light

Quantity

1 mg

Description

97% by HPLC

Molecular Formula

C55H80N16O16

Solubility

H2O or 5% Acetic Acid

Form

Lyophilized

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Description

  • The widely used MMP substrate FS-1 (Cat
  • No.03-32-5032) is modified by an N-terminal lysine elongation to produce a broad-spectrum MMP and TACE substrate that displays improved water solubility and substrate sensitivities
  • Exhibits 2- to 9-fold higher specificity constant (k cat /K m ) towards MMP-1, -8, -13, -14 when compared with FS-1 and ∽2-fold higher k cat /K m towards TACE when compared with TACE Substrate II and III (Cat
  • Nos
  • 616402 and 616403, respectively)
  • It has been used successfully in detecting T98G glioma cell surface-associated MMP activity and is shown to be resistant to proteolysis by human leukocyte elastase, trypsin, and ADAM-10.