47-588-95MG
MilliporeSigma™ Calbiochem™ MK-886
Manufacturer: MilliporeSigma™
CAS Number: 118414-82-7
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 47-588-95MG-Each-of-1 | In Stock | ₹ 16,024.53 |
47-588-95MG - Each of 1
In Stock
Quantity
1
Base Price: ₹ 16,024.53
GST (18%): ₹ 2,884.415
Total Price: ₹ 18,908.945
Color
White
Target Proteins
leukotreine biosybthesis
Molecular Formula
C27H33ClNO2S·Na
Solubility
DMSO or EtOH
Quantity
5 mg
Description
99% by TLC
CAS
118414-82-7
Formula Weight
494g/mol
Form
Solid
Other Options
| Image | Product Name | Manufacturer | Price Range | |
|---|---|---|---|---|
 | Enzo Life Sciences MK-886, (5mg), CAS Number: 118414-82-7 | -- | ₹ 11,020.13 | |
| | Enzo Life Sciences MK-886 (25mg). CAS: 118414-82-7 | -- | ₹ 44,087.36 | |
| | eMolecules Medchem Express / MK-886 / 5mg / 446263888 / HY-14166 / / 118414-82-7 / MFCD00876710 / 472.080 / C27H34ClNO2S | -- | ₹ 10,075.55 |
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Description
- A cell-permeable, orally active NSAID (nonsteroidal antiinflammatory drug) that blocks cellular Cox pathway PGE2 (prostaglandin E 2 ) production by inhibiting COX-1 and mPGES-1 (microsomal PGE 2 synthase-1), but not COX-2, activity (IC 50 = 8, 2, and 58μM, respectively), as well as suppresses cellular 5-LO (5-Lypoxygenase; Cat
- No
- 437996) pathway activation by inhibiting FLAP (5-LO-activating protein), rather than 5-LO, activity (<10% by 1μM MK-886)
- Unlike NSAIDs (nonsteroidal antiinflammatory drugs) that target only COX pathway, MK-886 does not cause gastrointestinal damages when applied in vivo .