50-060-90001

MilliporeSigma™ Calbiochem™ Temozolomide

Manufacturer: MilliporeSigma™

Select a Size

Pack Size SKU Availability Price
Each of 1 50-060-90001-Each-of-1 In Stock ₹ 15,749.88

50-060-90001 - Each of 1

₹ 15,749.88

In Stock

Quantity

1

Base Price: ₹ 15,749.88

GST (18%): ₹ 2,834.978

Total Price: ₹ 18,584.858

Color

Off-white

Target Proteins

DNA guanine residues

Formula Weight

194.2g/mol

Content And Storage

Protect from light

Quantity

50 mg

Description

99% by HPLC

Molecular Formula

C6H6N6O2

Solubility

DMSO

Form

Solid

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Description

  • A cell-permeable, orally bioavailable, blood-brain barrier-permeant MTIC [5-(3-methyltriazen-1-yl-)-imidazole-4-carboxamide] prodrug whose in vivo DNA alkylating activity is employed in anticancer therapy
  • MGMT ( O 6 -methylguanine DNA methyl transferase) repairs TMZ-damaged DNA lesion by covalently transferring O 6 -methylation on guanine residues to a cysteine residue on the MGMT, forming the basis of TMZ-resistance in cancer treatment
  • Please note that the molecular weight for this compound is batch-specific due to variable water content
  • Please refer to the vial label or the certificate of analysis for the batch-specific molecular weight
  • The molecular weight provided represents the baseline molecular weight without water.