50-447-90001
MilliporeSigma™ Calbiochem™ JNJ 16259685
Manufacturer: MilliporeSigma™
The price for this product is unavailable. Please request a quote
Color
White
Target Proteins
mGlu1
Formula Weight
325.41g/mol
Content And Storage
Protect from light
Quantity
5 mg
Description
98% by HPLC
Molecular Formula
C20H23NO3
Solubility
DMSO
Form
Solid
Related Products
Description
- An extremely potent, non-competitive antagonist for mGlu receptor subtype 1 (K i = 0.34nM; IC 50 = 0.55nM)
- 400-fold more selective for mGlu 1 than for mGlu 5 and no interaction with mGlu 2 , mGlu 3 , mGlu 4 , mGlu 6 , AMPA or NMDA receptors (IC 50 >10μM)
- Centrally active following systemic administration
- Widely used for studying substance abuse, learning and memory, and neural plasticity.