50-598-10001
MilliporeSigma™ Calbiochem™ PK11195
Manufacturer: MilliporeSigma™
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 50-598-10001-Each-of-1 | In Stock | ₹ 9,683.68 |
50-598-10001 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 9,683.68
GST (18%): ₹ 1,743.062
Total Price: ₹ 11,426.742
Color
White
Target Proteins
peripheral bezodiazepine receptor
Solubility
DMSO
Form
Solid
Description
98% by HPLC
Molecular Formula
C21H21ClN2O
Content And Storage
Protect from light
Quantity
10 mg
Related Products
Description
- An isoquinoline carboxamide that acts as a potent ligand for peripheral bezodiazepine receptor (K d = 20nM)
- Exhibits anti-inflammatory properties
- Binds to monocytes and following lesioning its binding up-regulated in brain macrophages and activated microglia
- Shown to enhance the susceptibility of cells to apoptosis induction by DNA damaging agents and can reverse the suppression of apoptosis by Bcl-2
- Serves as a ligand of the outer membrane translocator protein and reduces mitochondrial transmembrane potential within 30 minutes of exposure (˜100μM).