50-615-510MG
MilliporeSigma™ Calbiochem™ Pifithrin-μ
Manufacturer: MilliporeSigma™
CAS Number: 64984-31-2
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 50-615-510MG-Each-of-1 | In Stock | ₹ 13,367.04 |
50-615-510MG - Each of 1
In Stock
Quantity
1
Base Price: ₹ 13,367.04
GST (18%): ₹ 2,406.067
Total Price: ₹ 15,773.107
Color
Off-white
Target Proteins
p53 interaction with Bcl-xL and Bcl-2 proteins
Molecular Formula
C8H7NO2S
Solubility
DMSO
Form
Solid
Description
95% by HPLC
CAS
64984-31-2
Formula Weight
181.2g/mol
Content And Storage
Protect from light
Quantity
10 mg
Other Options
| Image | Product Name | Manufacturer | Price Range | |
|---|---|---|---|---|
 | Selleck Chemical LLC Pifithrin- 10mg 64984-31-2 NSC 303580, PFT | -- | ₹ 9,959.18 | |
| | eMolecules Medchem Express / Pifithrin- / 10mg / 446259565 / HY-10940 / / 64984-31-2 / MFCD00181531 / 181.210 / C8H7NO2S | -- | ₹ 10,075.55 | |
| | Medchemexpress LLC Pifithrin-μ | 64984-31-2 | MFCD00181531 | 10 mM * 1 mL in DMSO | -- | ₹ 7,905.74 | |
| | 64984-31-2 | 2-Phenylacetylenesulfonamide | -- | ₹ 4,192.44 - ₹ 38,502.00 |
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Description
- A cell-permeable sulfonamide that blocks p53 interaction with Bcl-xL and Bcl-2 proteins and selectively inhibits p53 translocation to mitochondria without affecting the transactivation function of p53
- Effectively protects against γ radiation-induced cell death in vitro and animal lethality in vivo
- Because Pifithrin-μ targets only the mitochondrial branch of the p53 pathway without affecting the important transcriptional functions of p53, it is superior to Pifithrin-α (Cat
- No
- 506132) in in vivo studies
- Shown to selectively interact with inducible HSP70 and disrupt its functions.