50-840-80001
MilliporeSigma™ Calbiochem™ InSolution™ Batimastat
Manufacturer: MilliporeSigma™
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 50-840-80001-Each-of-1 | In Stock | ₹ 12,341.17 |
50-840-80001 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 12,341.17
GST (18%): ₹ 2,221.411
Total Price: ₹ 14,562.581
Formulation
A 25 mM (2mg/168μL) sterile-filtered solution of Batimastat in DMSO.
Target Proteins
MMPs
Formula Weight
477.6g/mol
Form
Liquid
Description
97% by HPLC
Molecular Formula
C23H31N3O4S2
Content And Storage
Avoid Freeze-Thaw Cycles, Hygroscopic, Protect from Light
Quantity
2 mg
Related Products
Description
- A Marimastat (Cat
- No
- 444289) type of peptidyl hydroxamate-based inhibitor that potently inhibits a broad-spectrum of metalloproteinases, including MMP-1, MMP-2, MMP-3/stromelysin, MMP-7/matrilysin, MMP-9, δMT1 (MMP-14 without TM domain), ADAM8, and ADAM17/TACE (IC 50 = 3, 4, 20, 6, 4, 2.08, 51.3, and 19 nM, respectively), by targeting both the substrate binding site and the active-site Zn 2+ , while being much less potent toward ACE (Angiotensin Converting Enzyme) or α-secretase (IC 50 = 1.6 and 3.3μM, respectively)
- Batimastat is widely used in studying the involvement of MMPs in cancinogenesis and non-cancer pathological processes both in cultures in vitro and in animals in vivo .